Mike Brown is ruled out for England v Ireland

England full-back Mike Brown has been ruled out of Sunday's RBS 6 Nations match against Ireland after suffering a setback in his recovery from concussion.

Brown suffered the injury in a clash of heads during the win over Italy.

England head coach Stuart Lancaster said: "Mike and our medical staff have been diligent during every step of the graduated return to play protocol and they will continue to work to get him back to full health."

Alex Goode is set to start in Brown's place

England and Ireland, who will meet in Dublin (3pm, live on RTÉ 2), are the only sides left in the championship with 100% records, Joe Schmidt's side seeing off France 18-11 last time out.

Brown's absence comes after Wales wing George North missed a match after he took two blows to the head in their Six Nations opener against England.

North has been recalled for Saturday's clash with France, though.

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